Platform

Clarity in Every Cell, Insight in Every Pixel

Where human-relevant models meet AI-driven phenomics to decode disease, accelerate discovery, and predict drug response — at scale.

Trusted by leading biopharma partners for predictive biology and custom studies.

AI-Driven

Accelerated Discovery

Compound Screening

De-Risking

Early Prediction

Human-Relevant Data

Discover Platform

Every cell tells a story. Every pixel holds a clue. But most platforms only see the surface. pixlbio combines high-fidelity human cell models with next-generation computational phenomics.

We capture billions of cell–pixel relationships, revealing subtle changes in cell state, mechanism of action, and therapeutic impact that others miss.

Our platform transforms cellular whispers into actionable intelligence. Disease mechanisms hiding in plain sight. Drug responses waiting to be unlocked. Target validation that actually validates.Whether you're screening compounds, mapping disease biology, or predicting clinical outcomes — we deliver the clarity you need. Faster, deeper, and more predictive than ever.

Problems We Solve

Discovery Dilemma: Reactive Guesswork or Predictive Intelligence?

For decades, drug discovery has been a high-stakes gamble. It’s time to change the game. Choose between the outdated, costly cycle of reaction and the new era of data-driven prediction.

Biological Relevance

Data Insight Depth

Timeline Impact

Cost Efficiency

Mechanistic Understanding

Scalability

Customization

The Old Way is Broken

Animal models, poor translation

Single-point readouts, basic understanding

Late failure, years wasted

Failed candidates affect budgets

Black box phenotypic shifts

Manual, low throughput

Standardized models

The pixlbio Way is Built to Predict

Human iPSC models, clinical relevance

AI phenomics, deep mechanism

Early insights, rapid iteration

Early de-risking and triaging with high-throughput

Clear phenotypic fingerprints

Automated, high-throughput

Tailored disease models

Biology, Captured

High-Content Imaging Across Diverse Cellular Systems

Every discovery starts with the cell. Our platform supports a wide range of biologically relevant models—from iPSC-derived (pixCells) and primary cells to engineered cell lines. Automated, high-content imaging captures thousands of morphological and functional features per cell, revealing complex biological responses across healthy, diseased, or custom contexts. This deep cellular profiling forms the foundation for true human-relevant insight.

AI-Powered

Precision

Phenomics

End-to-End

Biology, Translated

Turning Cellular Complexity into Quantifiable Data

Advanced computer vision and AI algorithms transform rich cellular imagery into structured phenotypic fingerprints. Each dataset becomes a digital reflection of biological behavior—measurable, comparable, and interpretable. By converting complex cell biology into precise data representations, we enable a scalable and unbiased understanding of how molecules modulate living systems.

Intelligence, Amplified

Predictive AI Models Informed by Health and Disease

Our deep learning models integrate phenotypic, molecular, and contextual metadata to predict efficacy, safety, and mechanism of action across diverse biological backgrounds. Trained on data spanning healthy and pathological states, the models detect subtle, non-linear relationships between compound structure and cellular outcome. This predictive layer empowers researchers to anticipate responses and de-risk decisions long before in vivo or clinical stages.

Data Stream

Algorithm

Imaging

Automation

Analysis

Insight, Delivered

Decision-Ready Outputs via SaaS Platform

The result is clarity from complexity. Our SaaS platform consolidates imaging and AI outputs into intuitive visualizations and reports tailored to your biology. Actionable insights flow seamlessly into your R&D pipeline—driving hypothesis validation, compound prioritization, and strategy refinement. From screening to candidate selection, we deliver data you can act on with confidence.

Predictive

Efficacy

Insights

Readouts

Output

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Benefits

We Turn Complex Biology Into Clear Insight

Pixlbio combines human cell models, automated imaging, and AI-powered phenomics to reveal what others miss — delivering speed, accuracy, and predictive clarity in every experiment.

Human-relevant biology

We develop iPSC-derived human-relevant cell models that more accurately reflect real patient biology, reducing the gap between preclinical discovery and clinical success.

pixCells

Scalable automation

From imaging to functional analysis, every step is automated, enabling high-throughput screening without sacrificing precision. This leads to superior readouts to fuel your predictive models. Robust and reproducible.

SaaS platform

Enabling partners to track experiments in real-time and run in-silico phenomic predictions—through secure, API-based access.

AI-driven insights

Our advanced phenomics pipeline analyzes billions of cell–pixel relationships, revealing subtle changes invisible to the human eye.

pixCellPainting

pixCellServices

Automation at the Core

Clarity from Complexity. Automation That Sees What Others Miss.

Our service automates key processes — from data collection to analysis and physical operations. This allows you to reduce time, reduce the human factor, and increase the accuracy of results.

Automated Experimentation

From Design to Execution — Fully Automated
Integrated robotics handle experimental setup, perturbations, and cell painting with precision and consistency. Every step — from sample handling to imaging — runs seamlessly, minimizing variability and human intervention.

Intelligent Data Generation

High-Quality, Reproducible Data — At Scale
Our platform captures and manages cellular data through automated imaging and quality control pipelines. AI ensures each dataset meets the highest standards for reproducibility, enabling confident discovery and scalable experimentation.

Predictive Modeling

From Phenotypic Signatures to Actionable Insights
Advanced AI models analyze complex phenotypic data to uncover mechanisms of action, identify potential toxicities, and predict drug responses. This transforms raw image data into predictive insights for safer, faster, and more effective drug development.

Real-world applications of Pixlbio

Applications

Early toxicity screening

Predict hepatotoxicity, cardiotoxicity, and off-target effects prior to animal studies.

Mechanism of action discovery

Map phenotypic fingerprints to known mechanisms or uncover new ones.

Hit triage & prioritisation

Rank candidates across donors and disease backgrounds.

Complex disease modeling

Evaluate compounds in MASLD, A1ATD, fibrosis, rare metabolic disease — or engineer your own model.

“pixlbio’s unique combination of large scale automated Cell Painting capability, the high quality of the generated data, as well as their expertise in AI and predictive modelling, made them an obvious choice for AstraZeneca.”

Bjarki Johannesson

Director of Safety Innovation, AstraZeneca

“pixlbio, was selected for the Sanofi iDEA-TECH Awards Program to receive Sanofi’s support for its project due to their demonstrated ability to develop high-quality predictive models from their exceptional data. Within the funded project, the pixlbio team showcased profound expertise in Cell painting for morphological profiling, automation, AI and predictive modelling, which truly validates them as deserving awardees.”

Bodo Brunner

Head of In Vitro Biology and Cell Sample Technologies, Sanofi

“pixlbio’s cellular models have significantly improved our Go-No/Go translational decisions across multiple programs over the years at Deep Genomics. The hepatic cell systems are far superior and physiologically relevant compared to commonly used cell lines. More recently, we have begun testing disease variant carrying models, further improving translatability of our screening systems. Working with both the BD and technical support teams at pixlbio has been an excellent experience. Response times have been very fast and technical support and information provided has been above and beyond on a regular basis. We are looking forward to working on additional systems coming from the pixlbio team.”

Denis Gallagher

Principal Scientist, Deep Genomics