Custom Models

Your cells. Our pixels. Infinite possibilities.

From your iPSC line or ours — we create hepatocytes that match your biology, your disease model, and your discovery goals.

Order your Custom pixCells™

Trusted by leading biopharma partners for predictive biology and custom studies.

Data & AI Analytics

Custom

Customization

CRISPR Precision

Reliability

About Custom Models

Not every question can be answered with an off-the-shelf model

That’s why pixlbio offers full customisation of our iPSC-derived hepatocytes — whether starting from our validated wild-type and disease lines, your proprietary donor cells, or CRISPR-engineered variants.

Tailored Genotypes

We build models for any genotype—from single SNPs to complex polygenic backgrounds or rare mutations. Ideal for target validation and personalized research.

Any iPSC Source

Integrate your proprietary donor lines or select patient iPSCs from our curated banks. Differentiation into your pixCell of choice.

CRISPR Precision

Precise genome editing to create isogenic pairs, knockout/knockin or model specific variants — with full validation of effects.

Proprietary Differentiation

Our differentiation protocols provide primary hepatocyte morphology and function at scale — stably and reproducibly.

Co-culture Options

Take your custom pixCells and co-culture them. Complex phenotypes at your fingterips.

Functional Validation

We design and validate your experiments and readouts so that your results are ready for regulatory and commercial steps.

Scalable Supply

Cryosupply and volume production — from small research batches to screening scales without loss of quality. Why not billions of cells?

Data & AI Analytics

Deliver structured data + AI analysis of phenotypic signatures, ready for integration into your pipelines and decision-making.

IP & Regulatory Ready

Confidential work with proprietary materials, donor tracking, and documented processes that simplify future regulatory use.

Beyond Standard Models

Our proprietary differentiation protocols and genome editing expertise enable scalable production of primary-like hepatocytes and stellate cells. Model any genotype or disease background—from rare mutations to complex polygenic traits—and build co-culture systems tailored to your biology.

“pixlbio’s unique combination of large scale automated Cell Painting capability, the high quality of the generated data, as well as their expertise in AI and predictive modelling, made them an obvious choice for AstraZeneca.”

Bjarki Johannesson

Director of Safety Innovation, AstraZeneca

“pixlbio, was selected for the Sanofi iDEA-TECH Awards Program to receive Sanofi’s support for its project due to their demonstrated ability to develop high-quality predictive models from their exceptional data. Within the funded project, the pixlbio team showcased profound expertise in Cell painting for morphological profiling, automation, AI and predictive modelling, which truly validates them as deserving awardees.”

Bodo Brunner

Head of In Vitro Biology and Cell Sample Technologies, Sanofi

“pixlbio’s cellular models have significantly improved our Go-No/Go translational decisions across multiple programs over the years at Deep Genomics. The hepatic cell systems are far superior and physiologically relevant compared to commonly used cell lines. More recently, we have begun testing disease variant carrying models, further improving translatability of our screening systems. Working with both the BD and technical support teams at pixlbio has been an excellent experience. Response times have been very fast and technical support and information provided has been above and beyond on a regular basis. We are looking forward to working on additional systems coming from the pixlbio team.”

Denis Gallagher

Principal Scientist, Deep Genomics